A Protocolised Approach to Mitochondrial Biology

Our Science

Mito Laboratories develops protocolised intervention frameworks designed to address complex metabolic and cellular dysfunction. Rather than pursuing single-target solutions or “magic bullets,” our approach applies coordinated pressure across mitochondrial, microbial, metabolic, and immune systems.

Scientific Foundation

• Mitochondrial Hijack & Microbial Symbiosis — Pathological states exploit mitochondrial dysfunction alongside microbial cooperation to sustain proliferation, immune evasion, and metabolic dominance.
• Broad-Spectrum Antimicrobial Support — Reduction of bacterial, fungal, and parasitic contributors that reinforce inflammatory and oncogenic metabolic environments.
• Integrative Systems Philosophy — Biology is treated as an adaptive, interdependent network rather than a collection of isolated targets.
• Small-Molecule Focus — Preference for low–molecular weight compounds with well-characterised bioavailability and intracellular access.

Mechanistic Targeting Framework

The platform is designed to exert simultaneous metabolic, survival, and immune pressure through coordinated pathway modulation:

• Bcl-2 inhibition — Disruption of apoptosis resistance
• MCT-1 inhibition — Interference with lactate export and metabolic coupling
• Lactate dehydrogenase inhibition — Suppression of glycolytic dominance
• Pyruvate dehydrogenase kinase inhibition — Restoration of oxidative metabolism
• AMPK activation / mTOR inhibition — Energy sensing recalibration and growth suppression
• Acidosis modulation — Disruption of acid-mediated invasion and immune suppression
• Immune activation — Enhancement of innate and adaptive immune engagement
• Antimicrobial pressure — Reduction of microbial oncogenic support
• Mitochondrial repair — Restoration of bioenergetic integrity and signaling fidelity

This is not a single compound, a one-size-fits-all intervention, or a promise of miracles — but a structured, evidence-informed framework designed for biological complexity.

About

Mito Laboratories was founded to translate emerging insights in mitochondrial biology, metabolism, and systems medicine into scalable, rational platforms.